Skip to main content
 
polyfluoroalkyl-substances2-512.jpg

Introduction

PFAS contamination in surface water and wastewater is a growing global concern, prompting the need for sensitive, efficient, and EPA-compliant analytical solutions. This is Part 2 of a 4-part application note series showcasing a robust LC-MS/MS workflow aligned with US EPA Method 1633, now applied to real-world water samples.

This installment demonstrates how PerkinElmer’s QSight® 500 LC/MS/MS systems, combined with automated dual-layer WAX/GCB SPE sample prep, deliver accurate detection of 40 PFAS compounds at low ng/L levels from both surface and municipal wastewater samples. The method not only meets EPA 1633 performance criteria but also improves lab throughput by enabling reduced sample volumes and streamlined workflows.

  • Covers field sample prep, extraction efficiency, and matrix effect evaluation
  • Validated with real surface and wastewater samples across Ontario
  • All PFAS recoveries meet EPA 1633 requirements, including PT sample confirmation

Download Part 2 to explore proven workflows, SPE enhancements, and field-tested results. Stay tuned for Parts 3 and 4, covering tissue and solid matrix applications.

 

Like what you're reading?

To view the full content, please answer a few questions.