Revision to General Chapter USP 857, which emphasized on performance specifications for UV-Vis Spectrometers (e.g. Lambda 365), on December 1st 2019 USP officially announced the amended chapter with new regulations on testing parameters. There are some major modifications made related to calibration parameters which will supersede the earlier method protocols that were practiced in the regulated environment of QA/QC lab. This PerkinElmer note gives a quick look at the parameter changes and additions to the test limits and wavelengths to be tested.