PerkinElmer

Pre-eclampsia Management

Today women expect doctors to offer effective prenatal care based on the latest research evidence and screening solutions. They want the best care possible throughout pregnancy. The consensus among caregivers and researchers is that timing matters more than ever in pre-eclampsia management. The earlier you identify women at high risk for pre-eclampsia, the better the outcome for mother and child.

Why to screen pre-eclampsia?

Pre-eclampsia is a disorder affecting 2-5% of pregnancies and is a leading cause of maternal and perinatal mortality and morbidity. The high risk of the more severe forms of preeclampsia - early-onset and preterm pre-eclampsia - could be predicted and prevented with early screening and subsequent treatment for high risk patients.

Predict to prevent pre-eclampsia

PerkinElmer’s DELFIA® Xpress PlGF 1-2-3 assay, used in the ground-breaking ASPRE study (Rolnik et al, 2017), is the most sensitive first trimester screening assay for preeclampsia to date. Screening with DELFIA® Xpress PlGF 1-2-3 assay before 13+6 weeks of gestation in combination with other biophysical markers and established risk factors, high risk women that are likely to develop preterm pre-eclampsia later in their pregnancy could be identified.

Aid in Diagnosis of Pre-eclampsia in the 2nd and 3rd trimester

During second and third trimesters of pregnancy, the DELFIA® Xpress sFlt-1 kit can be used for predicting the onset of pre-eclampsia and to manage pre-eclampsia in combination with the PlGF 1-2-3 assay as a ratio of concentrations and with other clinical factors.

In addition to DELFIA® Xpress, the PlGF 1-2-3 assay is also available for PerkinElmer’s AutoDELFIA® and Victor2™ D platforms. PerkinElmer’s biochemistry assays and supporting instruments are complemented by essential items such as human serum controls to ensure the integrity of results. We also supply dedicated pre-eclampsia screening software for risk calculations. Together, these products constitute a complete solution for pre-eclampsia management.

PerkinElmer does not endorse or make recommendations with respect to research, medication, or treatments. All information presented is for informational purposes only and is not intended as medical advice. For country specific recommendations please consult your local health care professionals. Products may not be licensed in accordance with the laws in all countries, such as the United States and Canada. Please check with your local representative for availability

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